Please Help!! How to repair this?

Hi guys, i use HDLoader 8.0a, the iso are stored in my HD.

All worked fine so now i have problems.

I dont see the HDLoader 8.0a in the game list, but i see in the game list of Winhiip.

When i try to delete this ISO, Winhiip Show this error.

http://img221.imageshack.us/img221/3109/hd80a1rc.jpg

When i close winhiip i open again, but when i click in the select drive button, dont show anything.

I try to transfer games but showme the same error again and again, i think its problem for my HD and i dont know how to repair please help me.

Thanks.