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Most of my friends who bought 60GB PS3's from Day 1 like I did have all had to send theirs back in due to either Blu Ray Failure (3 of them) or YLOD (8 of them). My friends 40GB (Exact Same design) has started shutting itself down automatically despite the vents being clean and the fan itself is working. Just like the Xbox 360's that will inevitably go RROD this PS3 will YLOD.
Before anyone says anything about good ventilation space etc I made sure that the vents were clean on mine and that NOTHING was too close to it to stop decent airflow getting to it. Mine died on me in January of this year. With the Slim's believe it or not the cooling system is better as the fan is located in a better place and actually works properley.... Bolting the fan onto the bottom of the motherboard wasnt exactly the wisest of moves by Sony for the Original PS3's.