I remember having Zelda for the SNES running through a USA to UK convertor.
Dear god... don't breathe on it or the cart would wobble and the game would crash!
Having said that, it looks like the PS Vita will be taking M2 cards... or MicroSD. My phone takes those... I've actually got an 8GB kicking around the house. That's along with it's own propritary cart format.
I like the idea of using cartridges myself. As other people have mentioned, the DS is doing fine with them.
60GB (120GB WD Scorpio Drive) PS3 (CECHA01, NTSC), 3.7OFW
60GB (640GB Samsung Drive) PS3 (CECHC04, PAL), Kmeaw 3.55, Repaired (Dead Laser)
PSP-1003 FAT, CFW5.00 M33-6 & Prometheus v2
X-Box 360 Xenon (JTAG'ed, 500GB HDD)