I've got a working backup of Uncharted 3 which I have ftp'd over to the PS3's internal hdd and put under the gamez folder.
I tried running it through multiman and it just doesnt run. I've tried various game setting options but when I run it I just get taken back to the xmb screen.
Running Rebug CEX 4.46 - tried in normal and rebug mode as well. Doesnt make any difference.
I have not split any of the files on the internal hdd.