Just tested Resident Evil 4 PAL through SMB and it works nice.
Videos are a bit hanging and the subtitles are out-of-sync, but if the USBLD can reach a higher Bandwith (in a secure way and without bloating the "drivers"), than this already would be a perfect alternative for Slim-Users (I suspect, both issues are resolved if USBLD reaches a higher bandwith...).
PS2 V7/DMS3 V2 (FW:2.4b7); Seagate Baracuda 200GB
PS2 V7/CC1.0 (FW:34 hacked v2 BM:2.1.6); Maxtor DiamondMAX9 PLUS 160GB
PS2 SCPH-30004R; NoMod+NoLaser
3xSony MC 8MB
MAX/Datel 16MB with Boot-CD
Custom FMCB 1.8b+ Beta-Build, my AIO 0.5, Sony&xRhino-Linux