I think you've landed in the wrong subforum, this is for discussion of Open PS2 Loader, which allows a real PS2 to load games from other sources than optical discs, as an open-source alternative (and oftten replacement, as it is generally more compatible) to things like HDLoader, USBAdvance, etc. and also allows loading games from a network-connected SMB/CIFS share (Windows-style sharing) which AFAIK is a feature exclusive to OPL. You may want to try the PS2 General Discussion forum here, or the official PCSX2 forums for detailed info, as I'm not that experienced with the intricacies of PS2 emulation.
However, I can give you a basic overview. PCSX2 requires two separate "things" to boot a game - a copy of the PS2's BIOS ROMs, and a copy of the game itself (I think PCSX2 can use a physical disc as well as an ISO image). The PS2 BIOS is only legally obtainable by dumping it from your own PS2 via homebrew, and is definitely outside the scope of OPL discussion (Google is your friend). The game disc itself can simply be ripped with ImgBurn to a standard ISO, nothing special required. Once you have both of these, you can point PCSX2 at the dumped BIOS ROMs and the game ISO, and it should hopefully boot the game, barring any incompatibility.
Chip-free/MC-free homebrew <3
FMCB 1.93 on MC for emergencies, NA
250GB HDD/FHDB 1.93/OPL 0.9.2 (GSM and non-GSM)/PS2 games, NO HDDOSD
80GB HDD/FHDB 1.93/POPStarter rev12/OPL644/GSM0.37/PS1 games, NO HDDOSD
SCPH-75001 (sitting idle, slims suck):
FMCB 1.92 on MC