If it's happening consistently with other known good DVD's, then I would look at either the application (grab any available updates for it) or the drive itself (clean it). You could also try using DVDDecrypter (it's a freebie) to generate an ISO and burn from there (in ISO mode, you run a Read session, then a Write session).
Another thing that could be an issue (although an extremely remote possibility) could be your power supply for your PC. I know it sounds weird, but I've had this problem before. The new graphics cards and CPU's produce a lot of heat. All the cooling gear in the new systems pull alot of voltage off the motherboard and drive cables. If voltage dips too far below 12/5 volts you can get weird issues with drives and memory. A P4/Athlon XP with more than 3 drives (other than floppy) and a high end graphics card can really tax the stock 300/350 watt power supplies. I always shoot for a 400/450 watt when designing rigs these days.
If it ain't broke don't try to fix it! But, hell if you can tweak that bastard just a little bit more....hehehe.