Yes, I had the same thing when trying to play the scene near the start of Uncharted 2 where you're trying to defend your boat from the pirates. Screen would go blank just as the action hotted up. There is a solution somewhere on this forum (I know because I read it), but it was months ago and a I can't recall exactly what the solution was. At a guess, I think it was something to do with the payload and/or manager. Try different payloads and then managers. Post back your results.
"We all agree your theory is crazy, but is it crazy enough?" - Neils Bohr